ASTM-E2524 › Historical Revision Information
Standard Test Method for Analysis of Hemolytic Properties of Nanoparticles
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Scope
1.1 This test method covers assessing the effect of nanoparticulate materials on the integrity of red blood cells.
1.2 This test method uses diluted whole blood incubated with nanoparticulate material and the hemoglobin released from damaged red blood cells is determined.
1.3 This test method is similar to Practice F 756
1.4 This test method is part of the in-vitro preclinical characterization and is important for nanoparticulate material that will contact the blood in medical applications.
1.5 The values given in SI units are to be considered as the standard.
1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
Significance and Use
p>This test method is one of a series of tests listed in Practice F 748
This test method is similar to Practice F 756
Keywords
hemolysis; nanoparticulate; plasma; whole blood; ICS Number Code 11.040.20 (Transfusion, Infusion); 71.100.01 (Products of the chemical industry in general)
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71.100.01 (Products of the chemical industry in general)
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Document Number
ASTM-E2524-08
Revision Level
2008 EDITION
Status
Superseded
Modification Type
New
Publication Date
Feb. 1, 2008
Document Type
Test Method
Page Count
5 pages
Committee Number
E56.03