SS-EN-ISO-21427-2 › Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2 Mixed population method using the cell line V79 (ISO 21427-2:2006)
SS-EN-ISO-21427-2
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2009 EDITION
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CURRENT
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Included in this current edition are the following subparts:
2009 EDITION - April 6, 2009
2009 EDITION CORRIGENDUM 1 - Aug. 21, 2013
2009 EDITION CORRIGENDUM 1 - Aug. 21, 2013
This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.
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Designation Name
SS-EN ISO 21427-2:2009
Revision Level
2009 EDITION
Status
Current
Publication Date
April 6, 2009
Language(s)
English
Page Count
36
International Equivalent
EN ISO 21427-2:2009(IDT); ISO 21427-2:2006(IDT)