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This document specifies a method to predict and quantify misuse of child restraint systems (CRS) called Misuse Mode and Effect Analysis (MMEA). Such misuse can degrade the performance of CRSs. As a predictive method it is intended to be applied by CRS manufacturers at an early stage, before the CRS is put into use by consumers. Being predictive implies the possibility of incompleteness and errors. Such errors can be reduced if the proposed method is supported by field studies (for example, according to ISO 13215-1) and panel method evaluation (for example, according to ISO 13215-2).