SS-EN-ISO-21427-2 Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2 Mixed population method using the cell line V79 (ISO 21427-2:2006)

SS-EN-ISO-21427-2 - 2009 EDITION - CURRENT


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This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.

To find similar documents by classification:

13.060.70 (Examination of biological properties of water Microbiology of water, see 07.100.20)

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Designation Name

SS-EN ISO 21427-2:2009

Revision Level

2009 EDITION

Status

Current

Publication Date

April 6, 2009

Language(s)

English

Page Count

36

International Equivalent

EN ISO 21427-2:2009(IDT); ISO 21427-2:2006(IDT)