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Scope

1.1 This guide describes some standard procedures applicable to the analysis of phencyclidine and its analogues using microcrystal tests.

1.2 These procedures are applicable to phencyclidme and its analogues which are present in solid dosage form or in a liquid form. They are not typically applicable to the analysis of phencyclidine and its analogues in biological samples.

1.3 This guide offers an organized collection of information or a series of options and does not recommend a specific course of action. This document cannot replace education or experience and should be used in conjunction with professional judgment. Not all aspects of this guide may be applicable in all circumstances. This ASTM standard is not intended to represent or replace the standard of care by which the adequacy of a given professional service must be judged, nor should this document be applied without consideration of a projects many unique aspects. The word "Standard" in the title of this document means only that the document has been approved through the ASTM consensus process.

1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Significance and Use

The technique produces a chemical-precipitation reaction between the phencyclidine or its analogues and the precipitating reagent. The habit and the aggregation of the crystals formed may be used to distinguish phencyclidine or its analogues from other drugs.

The technique can be utilized on phencyclidine or its analogues present in either the salt or free base form.

The technique does not distinguish between salt and free base forms.

Keywords

microcrystalline testing; morpholine analogue of phencyclidine, PCM; phencyclidine, PCP; pyrrolidine analogue of phencyclidine, PCPy; thiophene analogue of phencyclidine, TCP; ICS Number Code 07.100.10 (Medical microbiology)

To find similar documents by ASTM Volume:

14.02 (General Test Methods; Forensic Psychophysiology; Forensic Sciences; Terminology; Conformity Assessment; Statistical Methods; Nanotechnology; Forensic Engineering; Manufacture of Pharmaceutical Products)

To find similar documents by classification:

07.100.10 (Medical microbiology Laboratory medicine, see 11.100)

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